Cheapest return flights from Chicago to Guatemala City in September from $289

AirHint found the following cheapest return flights from Chicago (MDW) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

20 Sep - 27 Sep Frontier Airlines
06 Sep - 20 Sep Frontier Airlines
15 Sep - 20 Sep Frontier Airlines
11 Sep - 16 Sep Delta
30 Sep - 07 Oct Delta
09 Sep - 30 Sep Delta
14 Sep - 22 Sep Delta
25 Sep - 28 Sep Delta
12 Sep - 15 Sep Frontier Airlines

Also check the deals for one-way flights from Chicago to Guatemala City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Guatemala City

Cheap car rent in Guatemala City

Feel free to contact us with any feedback or request another flight research.