Cheapest return flights from Chicago to Istanbul in October from $1046

AirHint found the following cheapest return flights from Chicago (MDW) to Istanbul (IST) in October 2025 (see full year).

Return flights

04 Oct - 18 Oct Frontier Airlines
02 Oct - 10 Oct Frontier Airlines
31 Oct - 22 Nov KLM
06 Oct - 01 Nov Frontier Airlines
02 Oct - 25 Oct Air France
15 Oct - 22 Oct Delta
31 Oct - 09 Nov Delta
01 Oct - 08 Oct Delta
19 Oct - 26 Oct Delta

Also check the deals for one-way flights from Chicago to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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