Cheapest return flights from Chicago to Santiago in December from $764

AirHint found the following cheapest return flights from Chicago (MDW) to Santiago (SCL) in December 2025 (see full year).

Return flights

02 Dec - 11 Dec LATAM Airlines Group
10 Dec - 13 Jan LATAM Airlines Group
27 Dec - 26 Jan LATAM Airlines Group
17 Dec - 27 Dec LATAM Airlines Group
24 Dec - 27 Dec LATAM Airlines Group
17 Dec - 28 Dec LATAM Airlines Group
17 Dec - 29 Dec LATAM Airlines Group
10 Dec - 20 Dec LATAM Airlines Group
19 Dec - 29 Dec LATAM Airlines Group
18 Dec - 29 Dec LATAM Airlines Group
19 Dec - 02 Jan Frontier Airlines
26 Dec - 04 Jan Frontier Airlines

Also check the deals for one-way flights from Chicago to Santiago in December.

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