Cheapest return flights from Chicago to Santiago in April from $652

AirHint found the following cheapest return flights from Chicago (MDW) to Santiago (SCL) in April 2026 (see full year).

Return flights

20 Apr - 27 Apr LATAM Airlines Group
17 Apr - 20 Apr Frontier Airlines
16 Apr - 20 Apr Delta
15 Apr - 20 Apr Delta
14 Apr - 21 Apr Delta
15 Apr - 22 Apr LATAM Airlines Group
15 Apr - 19 Apr LATAM Airlines Group
16 Apr - 19 Apr LATAM Airlines Group
02 Apr - 17 Apr LATAM Airlines Group
04 Apr - 13 Apr LATAM Airlines Group

Also check the deals for one-way flights from Chicago to Santiago in April.

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