AirHint found the following cheapest return flights from Madinah (MED) to Karachi (KHI) in September 2025 (see full year).

Return flights

27 Sep - 28 Oct	Gulf Air
24 Sep - 18 Oct	Gulf Air
15 Sep - 22 Sep	Gulf Air
29 Sep - 30 Oct	Gulf Air
01 Sep - 10 Oct	Gulf Air
04 Sep - 07 Sep	Gulf Air
02 Sep - 15 Oct	Flynas
16 Sep - 23 Sep	Flynas
30 Sep - 10 Oct	Flynas
17 Sep - 24 Sep	flydubai
15 Sep - 23 Sep	flydubai
22 Sep - 24 Sep	Jazeera Airways
02 Sep - 05 Sep	Flynas
03 Sep - 05 Sep	flydubai
15 Sep - 23 Sep	Flynas	direct
08 Sep - 15 Sep	flydubai
29 Sep - 30 Oct	Flynas	direct

Also check the deals for one-way flights from Madinah to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madinah to Karachi in September from $277

Return flights