AirHint found the following cheapest return flights from Melbourne (MEL) to Karachi (KHI) in October 2025 (see full year).

Return flights

22 Oct - 24 Oct	AirAsia X
04 Oct - 24 Oct	AirAsia X
31 Oct - 07 Nov	AirAsia X
31 Oct - 10 Nov	AirAsia X
22 Oct - 07 Nov	AirAsia X
22 Oct - 10 Nov	AirAsia X
22 Oct - 31 Oct	AirAsia X
24 Oct - 07 Nov	AirAsia X
24 Oct - 10 Nov	AirAsia X
24 Oct - 31 Oct	AirAsia X
22 Oct - 27 Oct	AirAsia X
24 Oct - 21 Nov	AirAsia X
24 Oct - 27 Oct	AirAsia X
01 Oct - 31 Oct	Qatar Airways
07 Oct - 21 Oct	Qatar Airways

Also check the deals for one-way flights from Melbourne to Karachi in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Karachi in October from $840

Return flights