AirHint found the following cheapest return flights from Mexico City (MEX) to Cali (CLO) in October 2025 (see full year).

Return flights

10 Oct - 17 Oct	Aeromexico	direct
01 Oct - 08 Oct	Aeromexico	direct
09 Oct - 18 Oct	Aeromexico	direct
02 Oct - 11 Oct	Aeromexico	direct
02 Oct - 17 Oct	Aeromexico	direct
11 Oct - 18 Oct	Aeromexico	direct
15 Oct - 22 Oct	Aeromexico	direct
07 Oct - 14 Oct	Aeromexico	direct
05 Oct - 13 Oct	Aeromexico	direct
04 Oct - 13 Oct	Aeromexico	direct
28 Oct - 10 Nov	Aeromexico	direct
29 Oct - 04 Nov	Aeromexico	direct
26 Oct - 02 Nov	Copa
28 Oct - 02 Nov	Avianca
28 Oct - 01 Nov	Avianca
25 Oct - 01 Nov	Viva
19 Oct - 01 Nov	Viva
18 Oct - 01 Nov	Viva
16 Oct - 01 Nov	Viva
24 Oct - 01 Nov	Viva

Also check the deals for one-way flights from Mexico City to Cali in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Cali in October from $221

Return flights