AirHint found the following cheapest return flights from Mexico City (MEX) to Rome (FCO) in September 2025 (see full year).

Return flights

26 Sep - 07 Oct	Aeromexico
24 Sep - 07 Oct	Aeromexico
25 Sep - 07 Oct	Aeromexico
08 Sep - 22 Sep	Aeromexico
15 Sep - 22 Sep	Air Canada
05 Sep - 18 Sep	Aeromexico
10 Sep - 17 Sep	Aeromexico
06 Sep - 20 Sep	Aeromexico
08 Sep - 10 Sep	Aeromexico
15 Sep - 30 Sep	Air Canada
17 Sep - 25 Sep	Air Canada
17 Sep - 30 Sep	Air Canada
08 Sep - 15 Sep	Aeromexico
16 Sep - 07 Oct	Air Canada
23 Sep - 01 Oct	Aeromexico
16 Sep - 08 Oct	United
25 Sep - 09 Oct	Aeromexico
30 Sep - 08 Oct	British Airways
14 Sep - 15 Oct	United
15 Sep - 15 Oct	United

Also check the deals for one-way flights from Mexico City to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Rome in September from $723

Return flights