AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

07 Oct - 15 Oct	Arajet
15 Oct - 22 Oct	Arajet
08 Oct - 15 Oct	Arajet
01 Oct - 06 Oct	Arajet
16 Oct - 20 Oct	Arajet
07 Oct - 13 Oct	Aeromexico	direct
20 Oct - 31 Oct	Aeromexico	direct
07 Oct - 15 Oct	Aeromexico	direct
07 Oct - 14 Oct	Aeromexico	direct
27 Oct - 31 Oct	Aeromexico	direct
15 Oct - 07 Nov	Aeromexico	direct
15 Oct - 03 Nov	Arajet
17 Oct - 02 Nov	Copa
30 Oct - 07 Nov	Copa
23 Oct - 11 Nov	Copa
19 Oct - 02 Nov	Aeromexico	direct
17 Oct - 02 Nov	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in October from $411

Return flights