AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

12 Oct - 17 Oct	Arajet
09 Oct - 13 Oct	Arajet
14 Oct - 22 Oct	Arajet
09 Oct - 22 Oct	Arajet
12 Oct - 20 Oct	Arajet
07 Oct - 17 Oct	Arajet
26 Oct - 07 Nov	LATAM Airlines Group
28 Oct - 04 Nov	LATAM Airlines Group	direct
29 Oct - 05 Nov	Avianca
28 Oct - 05 Nov	Avianca
01 Oct - 17 Oct	Arajet
29 Oct - 05 Nov	Aeromexico	direct
21 Oct - 26 Nov	Aeromexico	direct
27 Oct - 05 Nov	Aeromexico	direct
28 Oct - 05 Nov	Aeromexico	direct
04 Oct - 24 Oct	Arajet
08 Oct - 13 Oct	Copa
06 Oct - 15 Oct	Copa
30 Oct - 11 Nov	Copa
20 Oct - 07 Nov	Copa

Also check the deals for one-way flights from Mexico City to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in October from $403

Return flights