AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in April 2026 (see full year).

Return flights

05 Apr - 21 Apr	Arajet
18 Apr - 28 Apr	Arajet
01 Apr - 08 Apr	Arajet
15 Apr - 22 Apr	Aeromexico	direct
23 Apr - 07 May	Aeromexico	direct
29 Apr - 05 May	Aeromexico	direct
28 Apr - 07 May	Aeromexico	direct
23 Apr - 29 Apr	Aeromexico	direct
16 Apr - 23 Apr	Aeromexico	direct
21 Apr - 30 Apr	Aeromexico	direct
23 Apr - 30 Apr	Aeromexico	direct
29 Apr - 06 May	Aeromexico	direct
01 Apr - 14 Apr	Arajet
30 Apr - 09 May	Avianca
29 Apr - 11 May	Copa
20 Apr - 21 Apr	Avianca
28 Apr - 03 May	Aeromexico	direct
29 Apr - 11 May	Aeromexico	direct
29 Apr - 10 May	Aeromexico	direct
30 Apr - 11 May	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Sao Paulo in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in April from $420

Return flights