AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

07 Sep - 15 Sep	Arajet
07 Sep - 22 Sep	Arajet
09 Sep - 17 Sep	Arajet
16 Sep - 22 Sep	Arajet
14 Sep - 22 Sep	Arajet
28 Sep - 13 Oct	Arajet
06 Sep - 15 Sep	Arajet
21 Sep - 05 Oct	Arajet
25 Sep - 29 Sep	Arajet
23 Sep - 29 Sep	Arajet
14 Sep - 24 Sep	Arajet
14 Sep - 10 Oct	Arajet
11 Sep - 22 Sep	Copa
26 Sep - 07 Oct	Copa
21 Sep - 01 Oct	Arajet
30 Sep - 07 Oct	Copa
22 Sep - 01 Oct	Copa
29 Sep - 05 Oct	Copa
30 Sep - 04 Oct	Copa
26 Sep - 11 Oct	GOL Linhas Aéreas

Also check the deals for one-way flights from Mexico City to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in September from $455

Return flights