AirHint found the following cheapest return flights from Mexico City (MEX) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

04 Sep - 08 Sep	Avianca
18 Sep - 23 Sep	Avianca
13 Sep - 23 Sep	Avianca
29 Sep - 30 Sep	Volaris	direct
26 Sep - 30 Sep	Avianca
19 Sep - 30 Sep	Avianca
09 Sep - 14 Sep	Avianca
05 Sep - 08 Sep	Avianca
29 Sep - 04 Oct	Volaris	direct
18 Sep - 30 Sep	Volaris	direct
04 Sep - 08 Sep	Volaris	direct
30 Sep - 21 Oct	Volaris	direct
29 Sep - 06 Oct	Avianca
26 Sep - 03 Oct	Avianca
30 Sep - 03 Oct	Volaris	direct
27 Sep - 05 Oct	Avianca
26 Sep - 03 Oct	Volaris Costa Rica	direct
29 Sep - 06 Oct	Aeromexico	direct
28 Sep - 05 Oct	Aeromexico	direct
26 Sep - 20 Oct	Avianca

Also check the deals for one-way flights from Mexico City to Guatemala City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Guatemala City in September from $218

Return flights