Cheapest return flights from Mexico City to Guayaquil in December from $393

AirHint found the following cheapest return flights from Mexico City (MEX) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

15 Dec - 11 Jan Avianca
04 Dec - 08 Dec Avianca
12 Dec - 09 Jan Avianca
13 Dec - 09 Jan Avianca
16 Dec - 13 Jan Copa
16 Dec - 12 Jan Avianca
28 Dec - 31 Dec Avianca
28 Dec - 09 Jan Avianca
27 Dec - 12 Jan Copa
27 Dec - 09 Jan Avianca
28 Dec - 05 Jan Copa
28 Dec - 06 Jan Copa

Also check the deals for one-way flights from Mexico City to Guayaquil in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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