AirHint found the following cheapest return flights from Mexico City (MEX) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

03 Oct - 10 Oct	Arajet
02 Oct - 09 Oct	Aeromexico	direct
03 Oct - 19 Oct	Aeromexico	direct
09 Oct - 18 Oct	Aeromexico	direct
27 Oct - 05 Nov	Aeromexico	direct
30 Oct - 07 Nov	Avianca
17 Oct - 24 Oct	Arajet
31 Oct - 05 Nov	Avianca
17 Oct - 24 Oct	Aeromexico	direct
08 Oct - 19 Oct	Aeromexico	direct
09 Oct - 16 Oct	Aeromexico	direct
14 Oct - 28 Oct	Aeromexico	direct
13 Oct - 21 Oct	Aeromexico	direct
29 Oct - 12 Nov	Aeromexico	direct
23 Oct - 07 Nov	Avianca
29 Oct - 03 Nov	Avianca	direct
24 Oct - 07 Nov	Copa
31 Oct - 10 Nov	Copa
28 Oct - 03 Nov	Avianca	direct
23 Oct - 07 Nov	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Rio Negro in October from $242

Return flights