AirHint found the following cheapest return flights from Mexico City (MEX) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec	Aeromexico	direct
03 Dec - 11 Dec	Aeromexico	direct
01 Dec - 15 Dec	Aeromexico	direct
05 Dec - 12 Dec	Aeromexico	direct
07 Dec - 14 Dec	Aeromexico	direct
02 Dec - 06 Dec	Avianca
05 Dec - 14 Dec	Aeromexico	direct
11 Dec - 23 Dec	Aeromexico	direct
07 Dec - 13 Dec	Avianca
05 Dec - 13 Dec	Avianca
23 Dec - 01 Jan	Avianca
26 Dec - 13 Jan	Copa
23 Dec - 01 Jan	Aeromexico	direct
30 Dec - 12 Jan	Avianca
30 Dec - 06 Jan	Aeromexico	direct
29 Dec - 03 Jan	Avianca
14 Dec - 04 Jan	Copa
27 Dec - 02 Jan	Avianca
18 Dec - 04 Jan	Copa
26 Dec - 02 Jan	Arajet

Also check the deals for one-way flights from Mexico City to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Rio Negro in December from $257

Return flights