AirHint found the following cheapest return flights from Mexico City (MEX) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

24 Sep - 27 Sep	Avianca
25 Sep - 28 Sep	Avianca
15 Sep - 19 Sep	Arajet
29 Sep - 10 Oct	Arajet
29 Sep - 06 Oct	Arajet
22 Sep - 30 Sep	Avianca
25 Sep - 02 Oct	Avianca
23 Sep - 30 Sep	Avianca
22 Sep - 29 Sep	Aeromexico
24 Sep - 29 Sep	Avianca
25 Sep - 29 Sep	Avianca
22 Sep - 25 Sep	Avianca
12 Sep - 19 Sep	Arajet
26 Sep - 02 Oct	Copa
27 Sep - 08 Oct	Copa
30 Sep - 15 Oct	Copa
24 Sep - 01 Oct	Copa
26 Sep - 01 Oct	Copa
30 Sep - 07 Oct	Copa
30 Sep - 08 Oct	Copa

Also check the deals for one-way flights from Mexico City to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Mexico City to Rio Negro in September from $225

Return flights