AirHint found the following cheapest return flights from Mexico City (MEX) to Prague (PRG) in October 2025 (see full year).

Return flights

18 Oct - 23 Oct	Volaris
17 Oct - 23 Oct	Volaris
16 Oct - 23 Oct	Volaris
09 Oct - 16 Oct	Volaris
01 Oct - 15 Oct	Viva
08 Oct - 15 Oct	Volaris
13 Oct - 20 Oct	Volaris
30 Oct - 06 Nov	Viva
01 Oct - 09 Oct	Viva
24 Oct - 06 Nov	WestJet
01 Oct - 08 Oct	Aeromexico
03 Oct - 09 Oct	Viva
27 Oct - 25 Nov	Air Canada
25 Oct - 01 Nov	Aeromexico
19 Oct - 07 Nov	Lufthansa
05 Oct - 16 Nov	Air France

Also check the deals for one-way flights from Mexico City to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Prague in October from $794

Return flights