Cheapest return flights from Mexico City to Panama City in October from $282

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in October 2025 (see full year).

Return flights

08 Oct - 15 Oct Aeromexico direct
01 Oct - 08 Oct Aeromexico direct
31 Oct - 08 Nov Aeromexico direct
29 Oct - 05 Nov Aeromexico direct
08 Oct - 16 Oct Aeromexico direct
08 Oct - 14 Oct Aeromexico direct
02 Oct - 06 Oct Aeromexico direct
02 Oct - 05 Oct Aeromexico direct
07 Oct - 14 Oct Aeromexico direct
06 Oct - 16 Oct Aeromexico direct
01 Oct - 06 Oct Aeromexico direct
30 Oct - 04 Nov Aeromexico direct
30 Oct - 05 Nov Aeromexico direct
31 Oct - 05 Nov Aeromexico direct
30 Oct - 06 Nov Aeromexico direct
31 Oct - 04 Nov Aeromexico direct
28 Oct - 19 Nov Aeromexico direct
24 Oct - 26 Oct Avianca
28 Oct - 01 Nov Avianca
07 Oct - 17 Nov Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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