Cheapest return flights from Mexico City to Panama City in October from $446

Best time to book flights for Mexico City (MEX) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in October 2025 (see full year).

Return flights

01 Oct - 08 Oct Aeromexico direct
15 Oct - 20 Oct Aeromexico direct
20 Oct - 26 Oct Aeromexico direct
21 Oct - 27 Oct Aeromexico direct
21 Oct - 28 Oct Aeromexico direct
31 Oct - 08 Nov Aeromexico direct
21 Oct - 29 Oct Aeromexico direct
16 Oct - 25 Oct Aeromexico direct
13 Oct - 18 Oct Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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