AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in November 2025 (see full year).

Return flights

20 Nov - 25 Nov	Aeromexico	direct
19 Nov - 27 Nov	Aeromexico	direct
25 Nov - 29 Nov	Avianca
17 Nov - 25 Nov	Aeromexico	direct
24 Nov - 01 Dec	Aeromexico	direct
27 Nov - 30 Nov	Avianca
07 Nov - 12 Nov	Aeromexico	direct
27 Nov - 04 Dec	Aeromexico	direct
18 Nov - 21 Nov	Avianca
15 Nov - 18 Nov	Avianca
01 Nov - 05 Nov	Avianca
19 Nov - 23 Nov	Avianca
20 Nov - 06 Dec	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Panama City in November from $283

Return flights