Cheapest return flights from Mexico City to Panama City in May from $339

Best time to book flights for Mexico City (MEX) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in May 2025 (see full year).

Return flights

17 May - 25 May Avianca
17 May - 24 May Avianca
14 May - 17 May Avianca
22 May - 29 May Avianca
12 May - 16 May Avianca
18 May - 24 May Avianca
17 May - 21 May Avianca
17 May - 26 May Avianca
08 May - 17 May Avianca
13 May - 13 May Avianca
30 May - 02 Jun Avianca
22 May - 05 Jun Avianca
27 May - 02 Jun Avianca
30 May - 02 Jun Copa direct
22 May - 05 Jun Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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