Cheapest return flights from Mexico City to Panama City in September from $352

Best time to book flights for Mexico City (MEX) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in September 2025 (see full year).

Return flights

12 Sep - 15 Sep Avianca
12 Sep - 19 Sep Avianca
11 Sep - 20 Sep Avianca
04 Sep - 07 Sep Aeromexico direct
11 Sep - 16 Sep Aeromexico direct
07 Sep - 13 Sep Aeromexico direct
12 Sep - 16 Sep Aeromexico direct
26 Sep - 07 Oct Aeromexico direct
11 Sep - 15 Sep Aeromexico direct
14 Sep - 18 Sep Aeromexico direct
05 Sep - 20 Sep Aeromexico direct
29 Sep - 17 Oct Copa direct

Also check the deals for one-way flights from Mexico City to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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