AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in June 2025 (see full year).

Return flights

24 Jun - 08 Jul	Copa
20 Jun - 02 Jul	Copa
24 Jun - 09 Jul	Copa
20 Jun - 26 Jun	Copa
20 Jun - 27 Jun	Copa
26 Jun - 03 Jul	Arajet
20 Jun - 04 Jul	Copa
20 Jun - 29 Jun	Copa
20 Jun - 30 Jun	Copa
24 Jun - 30 Jun	Copa
23 Jun - 06 Jul	Copa
26 Jun - 27 Jul	Avianca
21 Jun - 26 Jul	Avianca
26 Jun - 10 Jul	Avianca
24 Jun - 29 Jun	Copa
18 Jun - 15 Jul	Volaris
19 Jun - 30 Jun	Avianca
21 Jun - 30 Jun	Avianca
21 Jun - 29 Jun	Copa
23 Jun - 28 Jun	Copa

Also check the deals for one-way flights from Mexico City to Santiago in June.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santiago in June from $538

Return flights