Cheapest return flights from Mexico City to Santiago in September from $424

Best time to book flights for Mexico City (MEX) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in September 2025 (see full year).

Return flights

11 Sep - 24 Sep Arajet
14 Sep - 24 Sep Arajet
09 Sep - 24 Sep Arajet
16 Sep - 01 Oct Arajet
30 Sep - 30 Oct Arajet
16 Sep - 25 Sep Arajet
09 Sep - 23 Sep Arajet
14 Sep - 27 Sep Arajet
16 Sep - 23 Sep Arajet
11 Sep - 21 Sep Arajet
02 Sep - 16 Sep Arajet
10 Sep - 24 Sep Volaris

Also check the deals for one-way flights from Mexico City to Santiago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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