AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in September 2026 (see full year).

Return flights

10 Sep - 23 Sep	Arajet
23 Sep - 30 Sep	Arajet
01 Sep - 15 Sep	LATAM Airlines Group
10 Sep - 17 Sep	Volaris
06 Sep - 13 Sep	Copa
11 Sep - 13 Oct	Copa
11 Sep - 18 Sep	Copa
16 Sep - 28 Sep	Copa
01 Sep - 09 Sep	Copa
13 Sep - 20 Sep	Copa
12 Sep - 20 Sep	Copa
29 Sep - 18 Oct	Viva
29 Sep - 14 Oct	Viva
24 Sep - 22 Oct	Avianca
29 Sep - 15 Oct	Viva
23 Sep - 14 Oct	Viva
26 Sep - 14 Oct	Viva
26 Sep - 15 Oct	Viva
29 Sep - 13 Oct	Viva
29 Sep - 16 Oct	Viva

Also check the deals for one-way flights from Mexico City to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santiago in September from $442

Return flights