AirHint found the following cheapest return flights from Mexico City (MEX) to Santo Domingo (SDQ) in September 2025 (see full year).

Return flights

26 Sep - 09 Oct	Arajet	direct
24 Sep - 29 Sep	Arajet
29 Sep - 06 Oct	Aeromexico	direct
21 Sep - 29 Sep	Aeromexico	direct
30 Sep - 07 Oct	Aeromexico	direct
18 Sep - 26 Sep	Aeromexico	direct
22 Sep - 29 Sep	Aeromexico	direct
26 Sep - 01 Oct	Arajet	direct
26 Sep - 02 Oct	Arajet	direct
26 Sep - 29 Sep	Arajet	direct
17 Sep - 01 Oct	Arajet	direct
17 Sep - 22 Sep	Arajet	direct
19 Sep - 22 Sep	Arajet	direct
16 Sep - 23 Sep	Arajet
27 Sep - 04 Oct	Aeromexico	direct
21 Sep - 28 Sep	Aeromexico	direct
24 Sep - 27 Sep	Arajet
27 Sep - 08 Oct	Copa
27 Sep - 08 Oct	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Santo Domingo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santo Domingo in September from $256

Return flights