Cheapest return flights from Mexico City to Santa Cruz in December from $549

AirHint found the following cheapest return flights from Mexico City (MEX) to Santa Cruz (VVI) in December 2025 (see full year).

Return flights

03 Dec - 18 Dec LATAM Airlines Group
03 Dec - 01 Jan Copa
03 Dec - 31 Dec Avianca
25 Dec - 20 Jan LATAM Airlines Group
12 Dec - 20 Dec Copa
25 Dec - 15 Jan LATAM Airlines Group
03 Dec - 06 Jan Avianca
24 Dec - 02 Jan Copa
18 Dec - 09 Jan Copa
31 Dec - 03 Jan Avianca
03 Dec - 03 Jan Copa

Also check the deals for one-way flights from Mexico City to Santa Cruz in December.

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