Cheapest return flights from Mexico City to Santa Cruz in May from $494

Best time to book flights for Mexico City (MEX) to Santa Cruz (VVI) flights at AirHint

AirHint found the following cheapest return flights from Mexico City (MEX) to Santa Cruz (VVI) in May 2025 (see full year).

Return flights

30 May - 06 Jun Copa
13 May - 20 May Copa
15 May - 20 May Aeromexico
14 May - 28 May Aeromexico
09 May - 17 May Copa
01 May - 09 May LATAM Airlines Group
14 May - 29 May Copa
01 May - 23 May LATAM Airlines Group
02 May - 18 May Avianca

Also check the deals for one-way flights from Mexico City to Santa Cruz in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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