AirHint found the following cheapest return flights from Minneapolis (MSP) to Rome (FCO) in September 2025 (see full year).

Return flights

03 Sep - 11 Sep	Icelandair
25 Sep - 09 Oct	Sun Country Airlines
02 Sep - 10 Sep	Sun Country Airlines
06 Sep - 13 Sep	Icelandair
22 Sep - 06 Oct	Icelandair
03 Sep - 25 Sep	Icelandair
08 Sep - 13 Oct	Icelandair
22 Sep - 02 Oct	Icelandair
23 Sep - 07 Oct	Icelandair
29 Sep - 13 Oct	Icelandair
07 Sep - 13 Sep	Icelandair
06 Sep - 11 Oct	Spirit Airlines
03 Sep - 11 Sep	Air France	direct
03 Sep - 25 Sep	Air France	direct
07 Sep - 13 Sep	Air France	direct

Also check the deals for one-way flights from Minneapolis to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Minneapolis to Rome in September from $525

Return flights