AirHint found the following cheapest return flights from Milano (MXP) to Panama City (PTY) in December 2025 (see full year).

Return flights

23 Dec - 31 Dec	Turkish Airlines
31 Dec - 10 Jan	Turkish Airlines
24 Dec - 03 Jan	Turkish Airlines
22 Dec - 14 Jan	Turkish Airlines
30 Dec - 09 Jan	Turkish Airlines
31 Dec - 09 Jan	Turkish Airlines
21 Dec - 05 Jan	Turkish Airlines
21 Dec - 03 Jan	Turkish Airlines
25 Dec - 03 Jan	Turkish Airlines
20 Dec - 10 Jan	Turkish Airlines
20 Dec - 05 Jan	Turkish Airlines
24 Dec - 31 Dec	Air France
20 Dec - 20 Dec	United

Also check the deals for one-way flights from Milano to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Panama City in December from $890

Return flights