AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in October 2025 (see full year).

Return flights

16 Oct - 26 Oct	Delta
02 Oct - 26 Oct	Delta
02 Oct - 21 Oct	Delta
03 Oct - 26 Oct	Delta
12 Oct - 19 Oct	Delta
02 Oct - 23 Nov	Delta
14 Oct - 20 Oct	Delta
24 Oct - 08 Nov	Delta
25 Oct - 15 Nov	LATAM Airlines Group
24 Oct - 21 Nov	LATAM Airlines Group
14 Oct - 12 Nov	LATAM Airlines Group
22 Oct - 31 Oct	LATAM Airlines Group
10 Oct - 18 Oct	Delta
24 Oct - 05 Nov	LATAM Airlines Group
04 Oct - 16 Oct	Delta
08 Oct - 29 Oct	LATAM Airlines Group
02 Oct - 14 Nov	Air France

Also check the deals for one-way flights from Milano to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in October from $826

Return flights