AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in December 2025 (see full year).

Return flights

16 Dec - 14 Jan	Air Canada
16 Dec - 19 Jan	Air Canada
16 Dec - 13 Jan	Air Canada
14 Dec - 14 Jan	Air Canada
14 Dec - 13 Jan	Air Canada
05 Dec - 09 Dec	Air Canada
12 Dec - 31 Dec	Air Canada
18 Dec - 14 Jan	Air Canada
18 Dec - 13 Jan	Air Canada
18 Dec - 12 Jan	Air Canada
06 Dec - 14 Dec	Delta
15 Dec - 15 Jan	Delta
14 Dec - 07 Jan	Air Canada
03 Dec - 23 Dec	British Airways
23 Dec - 30 Dec	Delta
11 Dec - 29 Dec	Delta
17 Dec - 30 Dec	Vueling Airlines

Also check the deals for one-way flights from Milano to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in December from $767

Return flights