AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in December 2025 (see full year).

Return flights

29 Dec - 29 Jan	Wizz Air Malta
30 Dec - 24 Jan	Delta
29 Dec - 17 Jan	Ryanair
16 Dec - 18 Jan	Aeroitalia
15 Dec - 17 Jan	Ryanair
16 Dec - 12 Jan	easyJet
31 Dec - 11 Jan	Turkish Airlines
24 Dec - 12 Jan	easyJet
15 Dec - 22 Dec	Ryanair
14 Dec - 15 Dec	Iberia
14 Dec - 20 Dec	Ethiopian Airlines
29 Dec - 08 Jan	Wizz Air Malta
23 Dec - 11 Jan	Ryanair
13 Dec - 18 Dec	Ryanair
18 Dec - 29 Dec	Ryanair
12 Dec - 31 Dec	Air Canada
16 Dec - 31 Dec	Air Canada
14 Dec - 31 Dec	Air Canada
18 Dec - 31 Dec	Ryanair
19 Dec - 31 Dec	easyJet

Also check the deals for one-way flights from Milano to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in December from $1371

Return flights