AirHint found the following cheapest return flights from Naples (NAP) to Istanbul (IST) in October 2025 (see full year).

Return flights

23 Oct - 26 Oct	Wizz Air
08 Oct - 13 Oct	Wizz Air Malta
07 Oct - 14 Oct	Wizz Air
30 Oct - 06 Nov	Wizz Air Malta
08 Oct - 14 Oct	Wizz Air Malta
09 Oct - 13 Oct	Wizz Air Malta
09 Oct - 14 Oct	Wizz Air Malta
20 Oct - 26 Oct	Wizz Air Malta
14 Oct - 21 Oct	Wizz Air
05 Oct - 06 Oct	easyJet
07 Oct - 08 Oct	Wizz Air
30 Oct - 03 Nov	Wizz Air Malta
31 Oct - 07 Nov	Aegean Airlines
30 Oct - 02 Nov	Wizz Air Malta
27 Oct - 01 Nov	Ryanair
26 Oct - 03 Nov	Wizz Air Malta
30 Oct - 04 Nov	Wizz Air Malta
28 Oct - 02 Nov	Wizz Air Malta
31 Oct - 08 Nov	Aegean Airlines
25 Oct - 01 Nov	Turkish Airlines

Also check the deals for one-way flights from Naples to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Naples to Istanbul in October from $145

Return flights