AirHint found the following cheapest return flights from New York (NYC) to Panama City (PTY) in October 2025 (see full year).

Return flights

22 Oct - 12 Nov	Spirit Airlines
22 Oct - 13 Nov	Spirit Airlines
27 Oct - 14 Nov	jetBlue
29 Oct - 14 Nov	jetBlue
23 Oct - 30 Oct	Volaris El Salvador
25 Oct - 30 Oct	Spirit Airlines
20 Oct - 01 Nov	jetBlue
24 Oct - 31 Oct	Spirit Airlines
25 Oct - 30 Oct	United	direct
27 Oct - 14 Nov	United	direct
29 Oct - 14 Nov	United	direct
26 Oct - 03 Nov	Copa	direct
22 Oct - 12 Nov	United	direct
22 Oct - 13 Nov	United	direct
23 Oct - 30 Oct	United	direct
24 Oct - 31 Oct	United	direct

Also check the deals for one-way flights from New York to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from New York to Panama City in October from $476

Return flights