AirHint found the following cheapest return flights from Porto (OPO) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

24 Sep - 21 Oct	Air Europa
23 Sep - 29 Oct	Air Europa
24 Sep - 25 Oct	Air Europa
20 Sep - 14 Oct	Air Europa
22 Sep - 31 Oct	Air Europa
06 Sep - 19 Oct	Air Europa
16 Sep - 09 Oct	Air Europa
09 Sep - 08 Oct	Air Europa
25 Sep - 12 Oct	Air Europa
19 Sep - 07 Oct	Iberia
19 Sep - 27 Sep	British Airways
18 Sep - 25 Sep	Air Europa
08 Sep - 15 Sep	Air Europa
09 Sep - 16 Sep	Air Europa
09 Sep - 27 Sep	Iberia
18 Sep - 26 Sep	Air Europa
19 Sep - 29 Sep	Air Europa
16 Sep - 26 Sep	Air Europa
08 Sep - 16 Sep	Air Europa
20 Sep - 28 Sep	Air Europa

Also check the deals for one-way flights from Porto to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Sao Paulo in September from $581

Return flights