AirHint found the following cheapest return flights from Porto (OPO) to Istanbul (IST) in April 2026 (see full year).

Return flights

23 Apr - 28 Apr	easyJet
27 Apr - 07 May	easyJet
21 Apr - 27 Apr	easyJet
18 Apr - 24 Apr	easyJet
22 Apr - 26 Apr	easyJet
17 Apr - 24 Apr	easyJet
30 Apr - 04 May	easyJet
11 Apr - 19 Apr	Vueling Airlines
22 Apr - 25 Apr	easyJet
16 Apr - 21 Apr	easyJet
10 Apr - 14 Apr	easyJet
30 Apr - 03 May	easyJet
21 Apr - 25 Apr	easyJet
27 Apr - 02 May	easyJet
25 Apr - 02 May	easyJet
23 Apr - 07 May	Vueling Airlines
23 Apr - 06 May	Vueling Airlines
21 Apr - 07 May	Vueling Airlines
16 Apr - 07 May	Vueling Airlines
16 Apr - 06 May	Vueling Airlines

Also check the deals for one-way flights from Porto to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Istanbul in April from $218

Return flights