AirHint found the following cheapest return flights from Porto (OPO) to Istanbul (IST) in April 2026 (see full year).

Return flights

09 Apr - 15 Apr	Lufthansa
29 Apr - 03 May	Ryanair
02 Apr - 05 Apr	Iberia
05 Apr - 08 Apr	Iberia
02 Apr - 09 Apr	Lufthansa
25 Apr - 02 May	Air Europa
05 Apr - 08 Apr	Turkish Airlines	direct
02 Apr - 09 Apr	Turkish Airlines	direct
09 Apr - 15 Apr	Turkish Airlines	direct
02 Apr - 05 Apr	Turkish Airlines	direct

Also check the deals for one-way flights from Porto to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Porto to Istanbul in April from $332

Return flights