AirHint found the following cheapest return flights from Porto (OPO) to Prague (PRG) in October 2025 (see full year).

Return flights

22 Oct - 29 Oct	Ryanair
21 Oct - 28 Oct	Ryanair
23 Oct - 28 Oct	Smart Wings
31 Oct - 03 Nov	Ryanair
29 Oct - 01 Nov	Vueling Airlines
23 Oct - 27 Oct	Smart Wings
25 Oct - 01 Nov	Ryanair
22 Oct - 26 Oct	Ryanair
30 Oct - 03 Nov	Ryanair
25 Oct - 28 Oct	Ryanair
24 Oct - 28 Oct	Ryanair
30 Oct - 05 Nov	Ryanair
28 Oct - 01 Nov	Ryanair
22 Oct - 04 Nov	easyJet	direct
22 Oct - 01 Nov	Vueling Airlines
30 Oct - 04 Nov	Ryanair
22 Oct - 28 Oct	easyJet	direct
31 Oct - 04 Nov	Ryanair
23 Oct - 26 Oct	Smart Wings
25 Oct - 27 Oct	Ryanair

Also check the deals for one-way flights from Porto to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Prague in October from $192

Return flights