AirHint found the following cheapest return flights from Porto (OPO) to Panama City (PTY) in October 2025 (see full year).

Return flights

13 Oct - 28 Oct	Air Europa
20 Oct - 04 Nov	Air Europa
24 Oct - 08 Nov	Air Europa
26 Oct - 10 Nov	Air Europa
14 Oct - 29 Nov	Air Europa
12 Oct - 27 Oct	Air Europa
23 Oct - 07 Nov	Air Europa
25 Oct - 09 Nov	Air Europa
28 Oct - 12 Nov	Iberia
27 Oct - 11 Nov	Air Europa
12 Oct - 17 Oct	Air Europa
31 Oct - 15 Nov	Air Europa
22 Oct - 06 Nov	Air Europa
11 Oct - 26 Oct	Air Europa
12 Oct - 24 Oct	Air Europa
05 Oct - 20 Oct	Air France
08 Oct - 23 Oct	Iberia
10 Oct - 25 Oct	Air Europa
06 Oct - 21 Oct	Air Europa
07 Oct - 22 Oct	Air Europa

Also check the deals for one-way flights from Porto to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Panama City in October from $678

Return flights