AirHint found the following cheapest return flights from Porto (OPO) to Panama City (PTY) in November 2025 (see full year).

Return flights

19 Nov - 04 Dec	KLM
05 Nov - 20 Nov	Air Europa
15 Nov - 30 Nov	Air Europa
15 Nov - 29 Nov	Air Europa
04 Nov - 19 Nov	KLM
02 Nov - 17 Nov	Air Europa
13 Nov - 28 Nov	Air Europa
14 Nov - 29 Nov	Air Europa
08 Nov - 23 Nov	United
12 Nov - 27 Nov	United
01 Nov - 16 Nov	Air Europa
16 Nov - 01 Dec	Iberia
22 Nov - 07 Dec	KLM
23 Nov - 01 Dec	Iberia
17 Nov - 02 Dec	Air Europa
20 Nov - 05 Dec	Air Europa
21 Nov - 06 Dec	Air Europa
23 Nov - 08 Dec	Air Europa
24 Nov - 09 Dec	Air Europa
26 Nov - 11 Dec	Air Europa

Also check the deals for one-way flights from Porto to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Panama City in November from $710

Return flights