AirHint found the following cheapest return flights from Porto (OPO) to Panama City (PTY) in September 2025 (see full year).

Return flights

09 Sep - 24 Sep	Air Europa
11 Sep - 24 Sep	Air Europa
08 Sep - 23 Sep	Air Europa
16 Sep - 25 Sep	Air Europa
10 Sep - 25 Sep	Air Europa
15 Sep - 27 Oct	Air Europa
16 Sep - 28 Oct	Air Europa
08 Sep - 22 Sep	Air Europa
15 Sep - 30 Sep	Air Europa
07 Sep - 22 Sep	Air Europa
11 Sep - 26 Sep	Air Europa
13 Sep - 28 Sep	Air Europa
20 Sep - 05 Oct	Air Europa
21 Sep - 06 Oct	Air Europa
22 Sep - 07 Oct	Air Europa
27 Sep - 12 Oct	Air Europa
19 Sep - 04 Oct	Air Europa
23 Sep - 08 Oct	Air Europa
28 Sep - 13 Oct	Air Europa
29 Sep - 14 Oct	Air Europa

Also check the deals for one-way flights from Porto to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Porto to Panama City in September from $558

Return flights