AirHint found the following cheapest return flights from Chicago (ORD) to Sao Paulo (GRU) in November 2025 (see full year).

Return flights

26 Nov - 03 Dec	United	direct
28 Nov - 05 Dec	United	direct
04 Nov - 18 Nov	Copa
14 Nov - 23 Nov	Copa
03 Nov - 10 Nov	Copa
04 Nov - 11 Nov	Copa
05 Nov - 12 Nov	Copa
06 Nov - 13 Nov	Copa
11 Nov - 18 Nov	Copa
12 Nov - 19 Nov	Copa
13 Nov - 20 Nov	Copa
18 Nov - 25 Nov	Copa
25 Nov - 02 Dec	Copa
19 Nov - 05 Dec	Spirit Airlines
20 Nov - 03 Dec	Copa
24 Nov - 01 Dec	Copa
27 Nov - 04 Dec	Copa
30 Nov - 07 Dec	Copa
20 Nov - 06 Dec	Copa
29 Nov - 06 Dec	Copa

Also check the deals for one-way flights from Chicago to Sao Paulo in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Sao Paulo in November from $475

Return flights