AirHint found the following cheapest return flights from Chicago (ORD) to Guatemala City (GUA) in April 2026 (see full year).

Return flights

10 Apr - 18 Apr	Avianca
13 Apr - 18 Apr	Avianca
24 Apr - 01 May	United
28 Apr - 19 May	United
29 Apr - 17 May	United
28 Apr - 04 May	United
24 Apr - 30 Apr	United
25 Apr - 30 Apr	United
25 Apr - 01 May	United
15 Apr - 22 Apr	Copa
13 Apr - 20 Apr	Copa
14 Apr - 21 Apr	Copa
15 Apr - 20 Apr	Copa
22 Apr - 06 May	Copa
07 Apr - 14 Apr	Spirit Airlines
17 Apr - 21 Apr	Copa
13 Apr - 01 May	Spirit Airlines
15 Apr - 05 May	Spirit Airlines
14 Apr - 05 May	Spirit Airlines
15 Apr - 01 May	Spirit Airlines

Also check the deals for one-way flights from Chicago to Guatemala City in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Guatemala City in April from $96

Return flights