Cheapest return flights from Chicago to Guayaquil in December from $619

AirHint found the following cheapest return flights from Chicago (ORD) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

11 Dec - 09 Jan Avianca
12 Dec - 09 Jan Spirit Airlines
12 Dec - 27 Dec Spirit Airlines
11 Dec - 27 Dec Spirit Airlines
25 Dec - 11 Jan Spirit Airlines
25 Dec - 09 Jan Spirit Airlines
20 Dec - 11 Jan Frontier Airlines
24 Dec - 11 Jan Spirit Airlines
12 Dec - 02 Jan Spirit Airlines
25 Dec - 27 Dec Spirit Airlines
24 Dec - 09 Jan Spirit Airlines
19 Dec - 02 Jan Copa
22 Dec - 03 Jan Copa
24 Dec - 27 Dec Spirit Airlines
22 Dec - 27 Dec Spirit Airlines
20 Dec - 27 Dec Spirit Airlines
19 Dec - 27 Dec Spirit Airlines

Also check the deals for one-way flights from Chicago to Guayaquil in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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