Cheapest return flights from Chicago to Guayaquil in April from $322

AirHint found the following cheapest return flights from Chicago (ORD) to Guayaquil (GYE) in April 2026 (see full year).

Return flights

15 Apr - 04 May Spirit Airlines
18 Apr - 06 May Spirit Airlines
21 Apr - 04 May Spirit Airlines
21 Apr - 06 May Spirit Airlines
27 Apr - 04 May Spirit Airlines
27 Apr - 12 May Spirit Airlines
27 Apr - 06 May Spirit Airlines
14 Apr - 04 May Spirit Airlines
30 Apr - 04 May Spirit Airlines
30 Apr - 12 May Spirit Airlines
08 Apr - 22 Apr Spirit Airlines
07 Apr - 22 Apr Spirit Airlines
15 Apr - 22 Apr Spirit Airlines
18 Apr - 22 Apr Spirit Airlines
21 Apr - 22 Apr Spirit Airlines
14 Apr - 22 Apr Spirit Airlines
07 Apr - 27 Apr Spirit Airlines
08 Apr - 27 Apr Spirit Airlines
15 Apr - 27 Apr Spirit Airlines
18 Apr - 27 Apr Spirit Airlines

Also check the deals for one-way flights from Chicago to Guayaquil in April.

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