Cheapest return flights from Chicago to Guayaquil in May from $289

AirHint found the following cheapest return flights from Chicago (ORD) to Guayaquil (GYE) in May 2026 (see full year).

Return flights

06 May - 12 May Spirit Airlines
12 May - 27 May Spirit Airlines
27 May - 02 Jun Spirit Airlines
20 May - 27 May Spirit Airlines
20 May - 02 Jun Spirit Airlines
09 May - 27 May Spirit Airlines
09 May - 12 May Spirit Airlines
18 May - 27 May Spirit Airlines
18 May - 02 Jun Spirit Airlines
06 May - 18 May Spirit Airlines
06 May - 15 May Spirit Airlines
12 May - 18 May Spirit Airlines
12 May - 15 May Spirit Airlines
26 May - 02 Jun Spirit Airlines
30 May - 02 Jun Spirit Airlines
15 May - 02 Jun Spirit Airlines
24 May - 02 Jun Spirit Airlines
21 May - 02 Jun Spirit Airlines
27 May - 05 Jun Spirit Airlines
20 May - 05 Jun Spirit Airlines

Also check the deals for one-way flights from Chicago to Guayaquil in May.

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