Cheapest return flights from Chicago to Istanbul in October from $604

AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in October 2025 (see full year).

Return flights

07 Oct - 22 Oct Frontier Airlines
12 Oct - 19 Oct Icelandair
06 Oct - 14 Oct Frontier Airlines
14 Oct - 21 Oct Spirit Airlines
05 Oct - 14 Oct Frontier Airlines
15 Oct - 27 Oct Spirit Airlines
15 Oct - 29 Oct Spirit Airlines
26 Oct - 15 Nov Frontier Airlines
31 Oct - 07 Nov TAP
20 Oct - 03 Nov Frontier Airlines
24 Oct - 07 Nov TAP
22 Oct - 15 Nov Spirit Airlines
13 Oct - 23 Oct Austrian Airlines
28 Oct - 03 Nov Air Canada
01 Oct - 25 Oct Frontier Airlines
10 Oct - 14 Oct WestJet
29 Oct - 02 Nov Spirit Airlines
29 Oct - 02 Nov Turkish Airlines direct
28 Oct - 03 Nov Turkish Airlines direct
20 Oct - 03 Nov Turkish Airlines direct

Also check the deals for one-way flights from Chicago to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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