AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in December 2025 (see full year).

Return flights

04 Dec - 11 Dec	Icelandair
13 Dec - 09 Jan	Icelandair
29 Dec - 12 Jan	Air France
08 Dec - 29 Dec	KLM
29 Dec - 15 Jan	Air France
30 Dec - 13 Jan	KLM
26 Dec - 09 Jan	Scandinavian Airlines
25 Dec - 06 Jan	Air France
13 Dec - 10 Jan	KLM
04 Dec - 10 Dec	Turkish Airlines	direct
27 Dec - 13 Jan	Air France
22 Dec - 17 Jan	KLM
24 Dec - 31 Dec	Air France
15 Dec - 03 Jan	Spirit Airlines
08 Dec - 29 Dec	Turkish Airlines	direct
20 Dec - 27 Dec	Air Serbia
24 Dec - 31 Dec	Turkish Airlines	direct
20 Dec - 28 Dec	Scandinavian Airlines
20 Dec - 27 Dec	Turkish Airlines	direct
20 Dec - 28 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Chicago to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in December from $575

Return flights