AirHint found the following cheapest return flights from Chicago (ORD) to Rio Negro (MDE) in May 2026 (see full year).

Return flights

19 May - 27 May	Spirit Airlines
20 May - 27 May	Spirit Airlines
20 May - 03 Jun	Spirit Airlines
18 May - 27 May	Spirit Airlines
11 May - 27 May	Spirit Airlines
18 May - 03 Jun	Spirit Airlines
19 May - 02 Jun	Spirit Airlines
15 May - 18 May	Copa
01 May - 09 May	Copa
03 May - 12 May	Copa
01 May - 10 May	Copa
02 May - 09 May	Copa
01 May - 05 May	Copa
18 May - 02 Jun	Spirit Airlines
20 May - 02 Jun	Spirit Airlines
17 May - 03 Jun	Spirit Airlines
17 May - 02 Jun	Spirit Airlines
15 May - 03 Jun	Spirit Airlines
15 May - 02 Jun	Spirit Airlines

Also check the deals for one-way flights from Chicago to Rio Negro in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Rio Negro in May from $250

Return flights