AirHint found the following cheapest return flights from Chicago (ORD) to Prague (PRG) in November 2025 (see full year).

Return flights

15 Nov - 22 Nov	Scandinavian Airlines
08 Nov - 14 Nov	Scandinavian Airlines
05 Nov - 19 Nov	Scandinavian Airlines
02 Nov - 16 Nov	Scandinavian Airlines
21 Nov - 13 Dec	Scandinavian Airlines
19 Nov - 13 Dec	Scandinavian Airlines
02 Nov - 09 Nov	Scandinavian Airlines
25 Nov - 02 Dec	SWISS
19 Nov - 29 Nov	Scandinavian Airlines
26 Nov - 01 Dec	SWISS
20 Nov - 13 Dec	Scandinavian Airlines
22 Nov - 29 Nov	Scandinavian Airlines
28 Nov - 06 Dec	United
26 Nov - 30 Nov	LOT
21 Nov - 26 Nov	United

Also check the deals for one-way flights from Chicago to Prague in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Prague in November from $421

Return flights