AirHint found the following cheapest return flights from Chicago (ORD) to Panama City (PTY) in January 2026 (see full year).

Return flights

22 Jan - 26 Jan	Spirit Airlines
28 Jan - 01 Feb	Spirit Airlines
31 Jan - 28 Feb	Spirit Airlines
23 Jan - 01 Feb	Spirit Airlines
24 Jan - 28 Jan	Spirit Airlines
22 Jan - 28 Jan	Spirit Airlines
08 Jan - 15 Jan	Avianca
31 Jan - 03 Feb	Avianca
22 Jan - 26 Jan	Copa	direct
28 Jan - 01 Feb	Copa	direct
31 Jan - 28 Feb	Copa	direct
22 Jan - 28 Jan	Copa	direct
24 Jan - 28 Jan	Copa	direct
09 Jan - 13 Jan	Spirit Airlines
09 Jan - 16 Jan	United
09 Jan - 16 Jan	Copa	direct

Also check the deals for one-way flights from Chicago to Panama City in January.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Chicago to Panama City in January from $487

Return flights