AirHint found the following cheapest return flights from Chicago (ORD) to Panama City (PTY) in August 2025 (see full year).

Return flights

20 Aug - 27 Aug	Spirit Airlines
23 Aug - 29 Aug	Spirit Airlines
21 Aug - 24 Aug	Spirit Airlines
23 Aug - 30 Aug	Spirit Airlines
17 Aug - 03 Sep	Spirit Airlines
22 Aug - 25 Aug	Spirit Airlines
07 Aug - 22 Aug	Spirit Airlines
22 Aug - 25 Aug	Copa	direct
21 Aug - 24 Aug	Copa	direct
12 Aug - 21 Aug	Copa	direct
21 Aug - 25 Aug	Copa	direct
17 Aug - 03 Sep	Copa	direct
28 Aug - 01 Sep	Copa	direct
29 Aug - 01 Sep	Copa	direct

Also check the deals for one-way flights from Chicago to Panama City in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Chicago to Panama City in August from $429

Return flights