AirHint found the following cheapest return flights from Orlando (ORL) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

15 Sep - 22 Sep	Avianca
24 Sep - 28 Sep	Avianca
23 Sep - 25 Sep	Avianca
11 Sep - 16 Sep	Avianca
24 Sep - 01 Oct	Avianca
17 Sep - 24 Sep	Avianca
30 Sep - 06 Oct	Avianca
23 Sep - 26 Sep	Copa
16 Sep - 24 Sep	Copa
18 Sep - 25 Sep	GOL Linhas Aéreas
24 Sep - 06 Oct	Avianca
13 Sep - 26 Sep	Avianca
18 Sep - 22 Sep	Avianca
14 Sep - 22 Oct	Avianca
25 Sep - 02 Oct	United
19 Sep - 02 Oct	United
21 Sep - 01 Oct	Delta
29 Sep - 13 Oct	Delta
30 Sep - 05 Oct	Avianca
20 Sep - 25 Oct	GOL Linhas Aéreas

Also check the deals for one-way flights from Orlando to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Orlando to Sao Paulo in September from $431

Return flights